 Artemisinin and its analogues are natural compounds with strong anti-cancer properties. They can reduce tumor size and slow down tumor growth in both animal models and human clinical trials. Their mechanism of action involves targeting specific proteins found in cancer cells, leading to apoptosis, cell death and prevention of further tumor growth. Further research is needed to understand how these compounds work and how they could be used to treat cancer. This article was authored by Maria P. Crespo Ortiz and Ming Q. Wei.