 The study compared two different methods of desizing fabrics, traditional chemical desizing and enzymatic desizing. Traditional chemical desizing uses harsh chemicals such as hydrochloric acid to remove sizing agents from the fabric. This method can cause damage to the fabric surface and reduce its quality. In contrast, enzymatic desizing uses enzymes produced by Bacillus Sirius AS2 bacteria to break down the sizing agents without damaging the fabric surface. The results show that enzymatic desizing is more effective than traditional chemical desizing, resulting in less fabric surface damage and better quality. Furthermore, the enzymatic desizing process takes much longer than the chemical desizing process, but the enzymes do not damage the fabric surface. This article was authored by Anila Rehman, Asma Saeed, Wajihar Assad, and others.