 All right. Thank you very much. Welcome to the Integrating Genomic Sequencing into Clinical Care, the CESAR and BEYON meeting. We're very pleased to have everybody here for the strategic planning slash program review meeting today. In light of this being such a full day and hopefully full of active discussion, we'd like to start out with introductions. So I'll go ahead and get started. My name is Lucia Hindorf. I am a program director in the Division of Genomic Medicine at NHGRI. We have so many people here, if people could just start with maybe just their name, affiliation and whether they're a CESAR investigator or not, that would be great. And then we can get to know each other more during the day. So Ben, how about let's start with you. Ben Wilfons, Seattle Children's Hospital, the co-PI of the CESAR project at Kaiser in Portland. Hi. I'm Pilar Osorio and University of Wisconsin, not a CESAR investigator. Can we grab Chinita real quick? Chinita, sorry to put you on the spot. I'm going to do a quick introduction. Chinita Hughes-Halbert, the medical university of South Carolina. Thanks. Steve Jaffee from University of Pennsylvania. I'm a Project 3 co-PI of the Dana-Farber CESAR project and also group chair of the LC group within CESAR. Matt Maite, University of Utah, not a CESAR investigator. Greg Cooper, I'm the PI of the Hudson Alpha CESAR project. I'm Jim Evans. I'm one of the PIs of the University of North Carolina CESAR. I'm Katrina Armstrong. I'm from MGH and I'm the chair of the CESAR advisory board. Sharon Plon, Baylor College of Medicine on PI with Will Parsons of the Baylor CESAR project. David Fiendstra University of Washington CESAR project. I'm Pat Teverka. I'm a researcher at the American Institute for Research and I'm not a CESAR investigator. Rusilo Onumashalu, University of California, San Diego. Bob Nussbaum, Invite Corporation, I'm not a CESAR investigator. Eric Green, NHGRI. Carolyn Hutter, NHGRI. Katrina Goddard from Kaiser Permanente Northwest in Portland, Oregon and on one of the co-PIs for the CESAR projects. Dan Macy's University of Washington and not a CESAR investigator. Heidi Rehm, Harvard Medical School and I'm with the MedSeq project with Robert Green. Ian Krantz from the University of Pennsylvania Children's Hospital of Philadelphia PI along with Nancy Spinner of the PDC CESAR project. I'm Dan Roden from Vanderbilt and I'm on the CESAR SAP. Deborah Leonard, University of Vermont, not CESAR. Levi Garroway, Dana Farber-Kansh Institute and Broad Institute, I'm the PI of the CANSEAC project, CESAR. Gail Jarvik, I'm the PI of the University of Washington CESAR project and co-PI of the Coordinating Center. I'm Elaine Lyon, University of Utah, AARUP Laboratories and I'm not a CESAR investigator but I'm on the advisory panel. Mary Rilling, St. Jude Children's Research Hospital, not CESAR. Arul Chenayan and I'm PI of the University of Michigan CESAR project on myoncassy. You and Ashley from Stanford Cardiologist and Geneticist and not a CESAR. We could only make the U so big and there are a number of people in the back so Alex could I ask you to take the mic and get the introduction started for the people in the seats back there. Thanks. Yeah, Alex Lee, NHGRI. Ellie Silverman, NHGRI. Brad Ozenberger, Gell Genome Institute of Washu and formerly involved in CESAR. Heather Junkins, NHGRI. Bob Wilden, NHGRI. Hi, I'm Eric Borewinkel from the University of Texas and also the Genome Center Baylor College of Medicine. I'm also on the Council for NHGRI. Yeah, I'm Ron Cardin. I'm at GSK. I'm also on NHGRI's Council. Mike Watson, American College of Medical Genetics and Genomics. Gene McEwen, NHGRI. Anastasia Wise, NHGRI. Greg Ferrell, Maine Dartmouth Family Medicine Residency Program. Sandy Aronson, Partners Healthcare. I participated in MedSeq and CSER EHR Working Group. Jeff Schloss, NHGRI. Prague Agarwal, PatientCenter.com Computer Institute. Hi, I'm Rex Chisholm, Northwestern University on the CSER CAP. Howard McLeod, Moffatt Cancer Center, former council member and just team Brutai instead of CSER. Barbara Bernhardt, University of Pennsylvania. I'm with the CHOP CSER Project. Kathy Wicklund, Northwestern University, non-CSER. Joe McInerney, American Society of Human Genetics. Sue Richards, OHSU. I'm on the Next Gen CSER Project. Naomi Aronson, Blue Cross and Blue Shield Association. Jonathan Berg, with the NC Genes Project at UNC. Gal Henderson, with the NC Genes Project at UNC. Barbara Kanig, University of California. I'm the PI of one of the return of results consortium projects. Bruce Korf, University of Alabama at Birmingham. Debbie Nickerson, University of Washington and also a CSER and also associated with Kaiser. Mike Smith, NHGRI. Charlize Kaganen, NCI. Sarah Skullen, Baylor College of Medicine and I'm on their CSER project. Mildred Choes, Stanford and the CSER Advisory Panel. Tracy Lively, National Cancer Institute. David Litwak, FDA. Wiley Burke, University of Washington and CSER Project. Molly Menir, NHLBI. Michael Hahn, NHGRI. Regina James, NICHD. Melissa Parisi, NICHD. Kelly Phillipski, NCI. Great. So as you can tell, we have a diverse and talented group here today. Before we get started with Eric Green's talk, I've been asked to give a few logistical announcements. So please be aware that we are webcasting this meeting. So everything that you say will be captured for all eternity. So the other thing is capital consulting staff. So can we have Sandra leave your hand? She and her staff will be at the registration desk all day if should you need anything. Box lunches, people should have received forms to pay for box lunches already. If you still have your form at your seat, please do not get up right now, but hold up your hand and somebody will come up and collect it for you. The hotel checkout is at noon. Transportation can be arranged by the hotel concierge. Please sign up right before the end of the meeting. We will have Wi-Fi. So hopefully you figured out the H meeting wireless network. And then finally, for those who like to tweet, you can follow along at hashtag Caesar and beyond, which is here at the bottom of the screen. OK, so with that, I think we're actually ready to get started with the meeting. And before I introduce Eric, I just wanted to point out some homework that I got from Eric Warwickle actually for me, which is to read this article in the Wall Street Journal about a family who had their genome sequenced and some hard decisions they had to make. So I think this is a very timely topic where, of course, I'll eager to talk about it today. And it's nice to know that it's getting some attention in the public and press as well. So without further ado, I'd like to introduce Eric Green, director of the NHGRI, who will talk to us about setting the context for this meeting. Thank you, Eric.