 Network Meta-Analysis, NMA, is a type of meta-analysis used to compare multiple treatments. It can be used to compare two or more treatments directly, as well as indirectly through a common comparator. NMA requires careful planning and execution, including defining the review question, specifying eligibility criteria, searching for and selecting studies, assessing risk of bias and quality of evidence, conducting a network meta-analysis and interpreting and reporting findings. This article was authored by Sing So Now, Vigilis Arupe S, Puhan Milo A, and others.