 Hello everyone, I am Sira Satish Kumar, Consultant Clinical Psychologist in the Department of Psychiatry in Manipal Hospital, Spangler. Well, there are a lot of research that shows momentary stress, which simply means momentary thoughts which are in the form of insecurities, brings physiological arousal in the person. Physiological arousal simply means increase skin conductance, increase heart rate variability, respiratory sinus arrhythmia. So, these are the signs that could be seen in the initial ways that leads to terminal illnesses. And when stress is prolonged for a longer time, and it becomes chronic in nature, it is seen that it has a huge manifestation in coronary diseases. And there are researchers that shows the mechanism behind stress and the coronary diseases. And the main mechanism involves the cortisol, how when cortisol is being produced in a persistent way, it leads to coronary heart diseases. And the autonomic hyperarousal also plays another primary mechanism in the coronary heart disease.