 This study examined the effects of normothermic machine perfusion on the immune system of donor organs. The researchers found that the immune cells present in the donor organs before perfusion were largely composed of neutrophils, which decreased significantly during perfusion. Additionally, the researchers observed an increase in the number of monocyte macrophage cells, which could be responsible for the information seen during perfusion. Overall, this study provides valuable insight into how the immune system responds to normothermic machine perfusion, which can help inform future intervention studies. This article was authored by T. Horts, S. Solcher, M. Fodor, and others.