A rocket has been fired at Jerusalem by Hamas - the first time the holy city is thought to have been targeted by Gaza militants using such a weapon.
Israeli police said the rocket landed in an open area near Gush Ezion, a collection of Jewish settlements in the West Bank southeast of the city.
The rocket caused no damage or injuries, the Jewish state's army said.
But an attack on what Israelis call their capital marks a significant escalation by Gaza militants, both for its symbolism and its distance from the Palestinian territory.
Located about 55 miles away from the Gaza border, Jerusalem had been thought to be beyond the range of Gaza rocket squads.
The armed wing of Hamas, Al Qassam Brigades, said on Twitter: "Al Qassam Brigades launch two M75 homemade missiles towards occupied Jerusalem."
Four Palestinians have been killed in a new Israeli strike on Gaza, a Hamas health ministry spokesman said, as multiple new raids struck throughout the territory.
Among the four to die was reportedly Ahmed Abu Jalal, a field commander of Hamas's armed wing.
Israeli border police officers detain a Palestinian demonstrator Israeli police detain a Palestinian during clashes in Jerusalem's Old City
Twenty-nine Palestinians - including 13 militants - have now been killed in the recent violence. Three Israelis were killed by a rocket on Thursday.
The Israeli military said nearly 200 rockets fired from Gaza hit Israel on Friday - half were intercepted by its Iron Dome anti-missile system.
Earlier on Friday, there was a second rocket attack by Palestinian militants on Tel Aviv in 24 hours.
Air raid sirens went off in the centre of Israel's largest city on Friday afternoon and people were forced to scramble for cover. There were no reports of any injuries and it is thought to have landed in the sea.
"We are sending a short and simple message: There is no security for any Zionist on any single inch of Palestine and we plan more surprises," Abu Obeida, spokesman for the Hamas militant wing, said of the rockets aimed at Israel's two main cities.
It was the second day in a row that a rocket from Gaza had reached the Tel Aviv area in what Israeli networks said was the first time rockets had been fired at the city since the 1991 Gulf War, when it was hit by Iraqi Scud missiles.
On Thursday, another rocket fell in the sea and the other landed in a Tel Aviv suburb, causing no damage or casualties. Israel responded with airstrikes.
