 The study aimed to investigate the role of micro-RNA, 5100, MANA, 5100, in all squamous cell cosonoma, OSCC, and its underlying mechanisms, finding that mere 5100 silencing inhibits proliferation, invasion and migration of OSCC cells via upregulating the expression of SCAI. This article was authored by Sicheng Wei, Baili Yu, Dacheng Hu, and others.