 Chikungunia fever, caused by Chikungunia virus, is a mosquito-borne disease with severe joint pain and inflammation that can last for more than one year and has a fatality rate of 0.4 to 0.5%. Despite being documented in over 100 countries, no licensed vaccine exists to prevent it. Various developments have entered clinical trials as potential options to fight this incapacitating disease since the late 1960s up until 2018. This article was authored by Arturo Reyes Sandoval.