 The glimphatic system is a fluid transport network of cerebrospinal fluid, CSF, entering the brain. CSF transport is facilitated by the expression of aquaporin-4, AQP-4, water channels. Mice with genetic deletion of AQP-4 exhibit abnormalities in the brain structure and molecular water transport. This article was authored by Wismt, Stefan, Gamalka, Lauren M. Hablitz, Wumberto Mestre, and others.