 D-Doscent is a new software package designed specifically for processing RAID-SAC data. It is faster than existing pipelines, such as stacks, and produces more accurate results by using both forward and reverse reads, including reads containing insertions or deletions. Additionally, it performs quality trimming rather than filtering, which allows for more accurate identification of variants between populations. This article was authored by Jonathan B. Piritz, Christopher M. Hollenbeck, and John R. Gold.