 The study assesses the causal involvement of infectious agents in different cancer types for the year 2012. It considers 10 carcinogenic agents including helicobacter pylori, human papillomavirus, hepatitis B virus, and Epstein-Barr virus. The study estimates that 2.2 million new cancer cases in 2012 were attributable to these infections with the most significant contributors being helicobacter pylori, human papillomavirus, hepatitis B virus, hepatitis C virus, and Epstein-Barr virus. The study also finds that the AFs for infection vary by country and development status with higher rates in sub-Saharan Africa. The study suggests that reducing the burden of cancer caused by infections is possible through population-based vaccination and screen and treat programs. This article was authored by Dr. Martin Plummer, Ph.D., Katharinda Martel, M.D., Jerome Vignad, Master of Science, and others.