 The Connect4Children C4C project is an initiative designed to help streamline the development of new medications for children. It provides a platform for multidisciplinary experts to offer advice to pharmaceutical companies who wish to conduct clinical trials involving children. This includes providing guidance on how to best design such trials, as well as ensuring that they are ethically sound and comply with regulatory requirements. The project also involves the participation of patients and their families, who can provide valuable insight into what works best for them. Since its launch in 2018, the project has been successful in providing advice to over 30 companies and has been praised by both the companies involved and the experts who have contributed to it. This article was authored by Catherine Cheng, Fenna Mala, Erja Lutza, and others.