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Vitamin B-12 ( Сyanocobalamin )

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Published on Nov 11, 2009

Vitamin B-12 is a water-soluble vitamin that is stored in the liver. Vitamin B-12 is a collective term for a group of cobalt-containing compounds known as corrinoids. The principal cobalamins are cyanocobalamin, hydroxocobalamin and the two coenzyme forms of Vitamin B-12, methylcobalamin and 5-deoxyadenosylcobalamin (adenosylcobalamin). Cyanocobalamin is the principal form of the vitamin used for fortification of foods and in nutritional supplements. Vitamin B-12 is also called cobalamin because it contains the metal cobalt. Vitamin B-12 is bound to the protein in food. Hydrochloric acid in the stomach releases B-12 from proteins in foods during digestion. Hydroxocobalamin is a man-made form of Vitamin B-12. The advantage using hydroxocobalamin is the lack of adverse effects seen with the nitrites such as methemoglobinemia and hypotension. It works by exchanging the hydroxy group for cyanide to form the non-toxic cyanocobalamin (Vitamin B-12).
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