 The IAIM implementation framework suggests that technology-based interventions such as text, email, EHR reminders, and social media campaigns can increase HPV vaccination coverage by being used together and mainstreamed into clinical and system-based practice. While text-based, email-based, and EHR reminders have the most evidence supporting their effectiveness, more studies are needed to demonstrate the impact of social media campaigns on HPV vaccine promotion. This article was authored by Ashley B. Stevens, Chelsea S. Nguyen, and Melissa S. Stockwell.