 Aging is associated with cognitive and biological degeneration, oxidative stress, and age-related diseases. Antioxidants can reduce oxidative stress by interrupting free radical propagation or inhibiting their formation, improving immune function and promoting healthy longevity. Understanding the molecular mechanisms of antioxidants involved in redox modulation of inflammation may provide a useful approach for potential interventions to promote healthy aging. This article was authored by B. Ling Tan, Muhammad E. S. A. Norhazan, Muhammad E. S. A. Norhazan, and others.