 In summary, our study found that cutaneous malignancies, mainly SCC and melanoma, were the leading cause of death in patients with dermatologic diseases at a third-level university hospital serving as a dermatology referral centre. Drug reactions were also a major cause of death, with sepsis being the most common immediate cause of death. This article was authored by Meena Saber, Geeta Fagihee, Sadmi Mohamed Sainthafori, and others.