 SARS-CoV-2 virus has mutated and multiple variants are generated by mutations are circulating in India as well as across the world. Let's discuss the SARS-CoV-2 variants which are circulating in India. When the most important of the variant is known as double mutant variant that is B.1.617. In fact, WHO has recently categorized it as a variant of concern. So what is so special or should I say concern about this variant? Well, as the name says it is a double mutant. That is this mutant has two key mutations each one of which has also been found in some other strains which have been found to be not so good. But take note even though the name suggests there are two mutations but in actuality there are more than 12 mutations. But it has been named so because these two Q mutations make this variant a variant of concern. So what are these mutations? Cust mutation is named as L452R which has also been found in some strains in California known as B.1.427 and B.1.429. This mutation increases the binding power of spike proteins with receptors on human cells. That means if there is an exposure to the virus there are high chances that we will get infected. Meaning that this makes the virus more transmissible increasing the infectivity rate. This mutation can also enhance the ability of the virus to multiply once the virus enters the cells. Now this mutation is made worse by the second mutation which is E484Q mutation. It is similar to a mutation found in a COVID variant in South Africa and Brazil which had been termed E484K. This mutation makes the SARS-CoV-2 variant a major immune escape variant. Meaning even if your body had been infected before with the original SARS-CoV-2 virus and it developed antibodies or worse even if you are vaccinated and have developed antibodies going to that this variant has the capacity to evade these antibodies. Well how is that possible? Well this is a mutation which occurs on spike proteins and are already formed antibodies against this code protein are not able to recognize the spike proteins and hence the virus can go and attach to the cells. So that means both mutations combined the virus can evade our immune system and has increased ability of transmission as well as replication inside our cells. So now a question of utmost importance is is the vaccine which has been made against the spike proteins of original SARS-CoV-2 virus effective against these variants or should we wait for some ideal vaccine? Well despite all this discussion the answer is resounding yes the vaccine is effective. How? Well the vaccine not only induces our body to produce antibodies it also activates our body to activate killer T cells which are the type of immune cells of our body these cells kill the infected cells of our body preventing the multiplication of the virus which uses our own nuclear machinery to multiply so if the infected cell is killed obviously the virus will not be able to multiply. So yes even though the virus can evade antibodies it's still activated killer T cells will be effective. So yes vaccine will be less effective true but it is better to get vaccinated than nothing and vaccine will also be able to prevent serious disease and decrease the chances of hospitalization because some cells have been activated in our body isn't it? In fact experts believe that because of this reason vaccination is effective for any or all variants circulating across the world. For more details on how vaccination acts you can check out the video given here at the top. Well friends hopefully the video helped you get convinced for getting vaccinated despite whatever variants are there. Thanks for watching the video do remember to share this video with others to spread the knowledge and do subscribe to the channel for more such updates thank you.