 This study found that a prebiotic supplement and high protein diet reduced body weight and modulated intestinal microbiota. The combination of these two diets resulted in greater energy conversion efficiency, leading to increased body mass compared to either diet alone. Additionally, the study showed that the prebiotic supplement had a positive impact on the gut microbiome composition, with higher levels of Bacteroids Prevotella bacteria and lower levels of Clostridium leptome. This article was authored by Francisco Koch, Michael Derno, Martina Langema, and others.