 Hyperglycemia, hyperglycemia, or high blood sugar also spelled hyperglycemia or hyperglycoma is a condition in which an excessive amount of glucose circulates in the blood plasma. This is generally a blood sugar level higher than 11.1 mL-litre 200 mg-dL but symptoms may not start to become noticeable until even higher values such as 15-20 mL-slash-L-tilde 250-300 mg-dL. The subject with a consistent range between tilde 5.6 and tilde 7 and mL-slash-L-100 to 126 mg-dL American Diabetes Association's guidelines is considered slightly hyperglycemic, while above 7 mL-litre 126 mg-dL is generally held to have diabetes. For diabetics, glucose levels that are considered to be too hyperglycemic can vary from person to person, mainly due to the person's renal threshold of glucose and overall glucose tolerance. On average however, chronic levels above 10 to 12 mL-slash-L-180 to 216 mg-dL can produce noticeable organ damage over time.