 This study examined the effects of cranberry extract on fasting blood glucose levels in a variety of genetically diverse mice. The results suggest that the efficacy of cranberry extract in lowering fasting blood glucose levels varies depending on the host's genetic background, gender, and diet. This suggests that a personalized medicine approach may be necessary when using cranberry extract as a therapeutic intervention. This article was authored by Fatima Amerisasu, Rana Tarebe, Itzak Ofek, and others.