 Skin wound healing involves a unique cellular function mechanism that restores tissue integrity but often results in limited wound repair. Ongoing studies aim to improve wound therapies, reduce costs, provide long-term relief, and effective scar healing through advanced treatment strategies such as scaffolds activated with growth factors, bioactive molecules, and genetically modified cells. This article was authored by Erika Maria Todely, Rossella Dorati, Ida Jenta, and others.