 Petroceol E has been found to be effective at inducing neuronal differentiation and combating oxidative stress. It does so by increasing the activity of NRF2, which leads to increased neuronal differentiation and decreased oxidative stress. This could lead to the development of new therapeutics based on petroceol compounds to treat neurodegenerative diseases. This article was authored by Jing Liu, Lin Lin Wang, Yu Guadu, and others.