 Hey everybody, Dr. O. This video we're going to talk about the basatracin. So basatracin is called the peptide antibiotics, so peptides would be short protein chains. The reason it's called basatracin, it was originally isolated from bacillus subtilis, a sorrel organism, from an actual wound from a patient named Tracy. So that's actually just kind of interesting where the name basatracin comes from. So it's a little different. It does block the production of cell wall, but it does it in a different way. It doesn't actually interfere with the production of the cell wall so much as the movement. So cell wall, pieces of cell wall are going to be produced inside the cell and then moved out to the cell, same way cell membranes are made. So this drug is actually going to block the movement of the precursors, the peptidoglycan cell wall precursors, from making it to where they're produced to the actual cell wall. So it is going to inhibit the production of new cell wall, which will kill the bacteria when they don't have a good enough cell wall. Basically osmosis will kill them at this point, the cell wall can't protect them if it's too weak. All right, it is a broad spectrum antibiotic. It's effective against both grand positives and grand negatives. The primary use though would be against grand positives skin organisms like staphylococcus and streptococcus. So you technically could use it orally or intramuscularly and occasionally it is, but it is nephrotoxic, meaning it can damage the kidneys. So it's primarily used with polymixin B and neomycin in what you would call the triple antibiotic or most commonly known by the brand name Neosporins. This would primarily be used topical in that way. So this neomycin, I have to think for a second, neomycin, polymixin B and basatracin are the three antibiotics in your triple antibiotic ointment or your neosporin. All right, so that is basatracin. That's primarily how it's used and that's what it does. I hope this helps. Have a wonderful day. Be blessed.