 This study aims to evaluate the effectiveness and safety of serious games for improving cognitive abilities among elderly people with cognitive impairment. The results suggest that serious games, including cognitive training games and exa games, are more effective than no intervention and conventional exercises for improving global cognition. However, the quality of evidence in all meta-analyses was very low due to several factors such as risk of bias, high heterogeneity, and imprecision of total effect sizes. Therefore, serious games should be considered as a complement rather than a substitute to existing interventions until further more robust evidence is available.