 Lyme disease can cause reversible dementia in some cases. In this particular case, a 75-year-old man presented with hallucinations, confusion, and aggression which were not responsive to anti-psychotic medication. He had a CT scan of his brain which was normal, but other tests revealed a rise in inflammation markers. The patient tested positive for Borrelia burgdorferi, a bacterium associated with Lyme disease, on a Western blot test. After being treated with appropriate antibiotics, the patient experienced a remarkable recovery. This case highlights the importance of considering Lyme disease as a possible cause of dementia, especially when there are no signs of CSF involvement. This article was authored by Chiara Sanchini, Chiara Papia, Chiara Kutaya, and others.