Ex-Vivo Lung Perfusion (EVLP)

Ex-Vivo Lung Perfusion (EVLP), where donor lungs are ventilated and perfused with acellular (non-blood) solution in a chamber, was introduced as a method to improve donor lung function and potentially increase the donor pool. This lung perfusion method, clinically applied by a group of University of Toronto, has demonstrated to improve the quality of donor lung that are deemed unacceptable as donor lung. Clinical trial is currently underway in several lung transplant centers in the United States. Attempts to improve donor lung function with this method have been made at Lung Transplant Program of University of Kentucky.

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