 This study demonstrated that the addition of silver nanoparticles, AGNPs, to graphene oxide, GO, sheets significantly enhanced their antimicrobial activity while maintaining their biocompatibility. Furthermore, the functionalization of GO sheets with polyvinyl pyrrolidone, PVP, increased their biocompatibility. These findings suggest that the combination of AGNPs and PVP could be used to create a new class of antimicrobial and biocompatible materials for various biomedical applications. This article was authored by Wafa A. Khalil, Haida H. A. Sherif, Bahari Hemdan, and others.