 Abstract consciousness emerges from the interactions between neural dynamics and regional specializations within the brain. It is characterized by a distinct signature that can be detected in both healthy and diseased brains. This signature is associated with increased activity in certain regions of the brain, as well as increased connectivity between these regions. Additionally, this signature is also linked to changes in brain state, such as those seen during psychedelic use or psychotic episodes. These findings suggest that abstract consciousness may be supported by efficient hierarchical processing constrained along a low-dimensional macroscale gradient. This article was authored by Eung Lee, Ha Young Liu, Shulei, and others.