 This study found that staff working in high-infection skilled nursing facilities were more likely to have been exposed to SARS-CoV-2 compared to staff working in lower-infection facilities. Additionally, certified nursing assistants and nurses were three times more likely to test positive for SARS-CoV-2 than non-clinical staff. These findings suggest that exposure to SARS-CoV-2 may be higher among healthcare workers in high-infection settings. This article was offered by Avnika Biamin, Joseph T. Kellogg, Carly Adams, and others.