 Dr. O'Hare. Dr. O'Hare. Everybody, Dr. O'Hare. So for this last video with the Integra Mentory System, I want to talk about repair of localized injuries to the skin. So it's basically a four-step process. Let's go ahead and dive in. So when you first cut yourself, during step one, you're going to have bleeding. So bleeding is going to bring this blood to the area that's going to end up clotting and scabbing here in just a moment, and at the same time, mast cells are going to release histamine. Histamine is very inflammatory, so you're going to get this bleeding response and inflammatory response. The inflammatory response is going to be drawing new cells to the area so they can do their jobs coming up. So that's going to be step one. Step two, you're going to have the clot formation. So the blood is going to clot, and you're going to have this scab that's going to form. The scab is going to stabilize this area, and it's going to be a temporary plug to hopefully keep microbes from entering. It's very important that this wound gets covered before an infection is going to set in. Also during this step, you're going to see germinative or stem cells starting to show up in the area. A few key cell players you see here see macrophages. Cells are going to come in and clean up the debris and get rid of the debris so new tissue can form. Fibroblasts are going to come in, and they're going to form the scar tissue to replace the tissue that was there. And then also you're going to see endothelial cells are going to come in to form this granulation tissue that's going to restore the vascular supply. So the blood supply is going to be restored to this area. Fibroblasts are going to lay down scar tissue to replace this tissue that was there. So the skin's going to be renewed, but not as good as it used to be. You'll still see a scar. And then we're going to have this area get cleaned up. So over time, the fibroblasts are going to keep replacing damaged tissue by laying down more scar tissue. The blood supply is going to be replenished here, and now we have this replacement skin if you want to call it that, but it's mainly scar tissue now. This scar tissue will continue to grow and thicken so you may see a raised cheloid, or at least see evidence of a scar in an area, but at least now we're not bleeding. There's not a pathway for pathogens to come in so the skin's been repaired. Now is it going to look beautiful? No, but your body doesn't care about that. Your body cares about keeping infections out and keeping blood in, and that's what scar tissue is great for doing, whether it's here in your skin or anywhere else. Scar tissue is the quickest way to heal something up well enough for you to get on with your life. All right, so that's how we repair damage to the skin. I hope this helps. Have a wonderful day. Be blessed.