 Treatment of multidrug-resistant tuberculosis, MDRTB, requires long courses of expensive medication which can be challenging due to the high risk of side effects. In this study, we examined the effectiveness of different treatment combinations, as well as the use of whole genome sequencing, WGS, in MDRTB cases. Of the 47 cases studied, 35-74% had a successful treatment outcome. Factors associated with non-successful outcomes included Finnish origin and XDRTB. Almost 90% of the cases experienced adverse events from at least one drug. Phenotypic and WGS drug-resistance results were fully concordant for isoniasid, fluoroquinolonies, amicacin, and greater than 90% concordant for rifampicin, pyrazinamide, cannamycin, and capryomycin. Additionally, more than 60% of phenotypically afambutal susceptible isolates were found to be genetically resistant. The results of the rifampicin and isoniasid. This article was authored by Verve Corhonen, Pia Kivala, Marjo Hampra, and others. We are article.tv, links in the description below.