 This study aimed to formulate a pharmaceutical dosage form containing omeprazole, OMP, and curcumin, CURC, to treat experimental peptic ulcers. OMP and CURC were preliminarily complexed with hydroxyperpill beta-cyclogextrin for enhancing their solubilization. After that, the combined complex, CURC slash OMP, was loaded to alginate beads to sustain their release and then coated with chitosan. Finally, we tested the antiosyrogenic impact of the best formula versus free OMP or OMP only loaded beads. The formulated spherical beads diameter range from a minimum value of 1.5 plus or minus 0.08 millimeters to 2.6 plus or minus 0.24 millimeters, the swelling results range from 400.00 plus or minus 8.5 percent to 800.00 plus or minus 6.2 percent. The entrapment efficiency was in a range from 60.85 plus or minus 1.01 percent to 87.44 plus or minus 1. This article was authored by Eman J. Heichel, Rashad M. Cowd, Shadeed Gad, and others. We are article.tv, links in the description below.