 Biomedicine and tissue regeneration have made significant advancements recently, which has had a positive effect on the entire healthcare spectrum. These advances have enabled the development of applications for restoring damaged tissues, resulting in their functionality being restored. Cardiac tissue engineering, CTE, which combines biomolecules, biomimetic scaffolds, and cells, plays a critical role in this process. Stimuli responsive hydrogels, SRHs, are excellent three-dimensional, 3D, biomaterials for tissue engineering, TE, and various biomedical applications. They can mimic the intrinsic tissues physical, chemical, and biological characteristics in a variety of ways. Additionally, they provide for 3D setup, adequate aqueous conditions, and the mechanical consistency needed for cell development. Furthermore, they function as competent delivery platforms for various biomolecules. Many natural and synthetic polymers were used to fabricate these intelligent platforms with innovative enhanced features and specialized capabilities that are suitable for CTE applications. In this review, different strategies employed for CTE were outlined. Limitations of the use of conventional This article was authored by Hussain M. L. Hussaini, Hussain M. L. Hussaini, Imman-e-Madi, and others. We are article.tv, links in the description below.