 Nanogenerators, INGs, which convert mechanical energy into electrical energy, have been used as a power source for cardiac electronic devices, CEDs. These devices can be used to treat and prevent heart diseases by providing continuous power without the need for battery replacement or other external sources of power. Recent advances in NG technology have led to improved performance of these devices, making them more suitable for use in medical applications. This review discusses the current state of research on NG-based CEDs, including Teng and Peng, and their potential applications in the field of medicine.