 This study found that patients who received combination anti-obesity medications, OMs, in addition to intensive lifestyle modifications had better weight loss outcomes compared to those who only received lifestyle modifications. The study also showed that patients who underwent RuanY gastric bypass, RyGB, surgery lost less weight than those who underwent vertical sleeve gastrectomy, VSG, or open RyGB surgeries. This article was authored by Gunter Wong, Erica M. Garner, Sahar Takush, and others. The study also showed that patients who underwent RuanY gastric bypass, RyGB, or open RyGB surgeries had better weight loss than those who underwent vertical sleeve gastrectomy, VSG, or open RyGB surgeries.