 Cell membrane coding technology is an approach to the biomimetic replication of cell membrane properties. Nanoparticles, N-piece, coated with cell membranes offer an opportunity to unite natural cell membranes' properties with those of the artificial inner-core material. The coated N-piece not only increased their biocompatibility, but also achieved effective and extended circulation in vivo. This article was authored by Yao Lu, Jing Shan Luo, Xiao Jia Chen, and others.