 Chlorogenic acid protects against myocardial ischemia reperfusion injury by reducing NLRP3 inflammasome-mediated pyroptosis through the suppression of LNC-neat-1 expression in vitro and in vivo, suggesting that targeting LNC-neat-1 may be a therapeutic strategy for myri. This article was authored by Xinchai, Zhengwei Liang, Zheng Shijong, and others.