 Hello everyone, myself Dr. Rohan Rajkumar More. I'm resident from the department of radiology at Dr. Vasantroporn Medical College, Nasik. MR imaging findings of corpus callosum is a case report. The origin of corpus callosum is a rare brain mass formation that can occur isolated or associated with other anatomical defects as a part of complex congenital syndrome. The defect is complete when total absence of corpus callosum occurs or partial when only certain regions of the structure are formed. Despite the gross anatomical consequences of this defect, a spectrum of neurological manifestations observed in individuals with urgenic use of corpus callosum varies from severe intellectual disability to normal intelligence. However, even in individuals with isolated urgenic use of corpus callosum and no evident neurological deficit, certain neuropsychological alterations may occur as cognitive demand increases with age. There appears to be male predilection. The male is to female ratio is 2 is to 1. Maternal alcohol consumption during pregnancy has been recognized as another risk factor. The introduction of corpus callosum is the largest commissure fiber in the brain and is essential for inter hemispheric integration of sensory motor and higher order cognitive information. It can be symptomatic or asymptomatic. Diagnosis is based on imaging brain. Clinical signs are variable. They may include mental retardation, more or less moderate seizures, then facial dysmorphism and hyperhidrosis. Treatment is purely symptomatic. Urgenesis is a result of an insert offering at approximately 8 to 12 weeks of gestation resulting in failure to form the corpus callosum. The white-minded tracts which usually cross midline instead are oriented vertically, separating the lateral ventricles widely, giving a racing car sign configuration. The development of corpus callosum occurs between the 12th and 16th to 20th weeks of gestation. Traditionally, it was believed that the development begins in the genu and progresses posteriorly with rostrum appearing last. The occurrence of urgenesis of corpus callosum is usually sporadic. Disturbance of embryogenesis in the first trimester of pregnancy by an unknown insult is sometimes put forward as probable antinatal cause. Urgenesis of corpus callosum can occur in other congenital anomalies, including unknown cheery malformation, dandy walker syndrome, schizanum kefali, icardi syndrome, polo-prosumum kefali and several trisomes. The case report, a 7-month-old female child presented with history of unable to hold neck, absent palmar and pincergrass and global developmental injury. The child was born at term with 5-day NICU stay and didn't cry immediately after birth. The child was born to healthy, unrelated parents. Family history was unreferable. On MRI brain imaging, entire corpus callosum was not visualized. Singulate sulcus was absent with medial hemispheric sulcus seen reaching up to the 3rd ventricle in radial fashion. Dialected high-riding 3rd ventricle and parallel configuration of lateral ventricles giving racing cars. These are the images which you can see on screen now. Here, the image on the right is T1-weighted sagittal image where absent singulate sulcus with medial hemispheric sulcus seen reaching the 3rd ventricle in radial fashion. The image on the left is T2-weighted image where there is parallel configuration of the lateral ventricles giving racing cars sign. And the rightmost image is T2-star coronal image where corpus callosum is absent and the image demonstrating the Moose head appearance. Now the discussion. The corpus callosum is the largest cerebral white matter commissure consisting of approximately 200 million axioms connecting different parts of right and left hemispheres. This structure is divided in five anatomical regions. That is genu rostrum, body, isthomas and sphenium. The corpus callosum contains homotopic and heterotopic interhemispheric nautracks establishing both excitatory and inhibitory connections. This allows bilateral communication between primary sensory motor areas and integration of cortical located on the contralateral or ipsilateral hemisphere. Trans callosum fibers are organized in separate nautracks along the sub regions of the corpus callosum according to the functional areas towards which they are projected. There is prefrontal, premotor and supplementary motor, primary motor, primary sensory, varietal lobe, temporal lobe and occipital lobe. A genesis of corpus callosum is rare condition which usually presents with clinical features such as seizures, feeding problems, development and delay, impaired hand coordination, impaired visual and auditory memory and sometimes with hydrocapillus. Though the condition can have a wide range of manifestations, in our case there was global development at the time of milestones without any gross physical or mental disability. No other congenital anomalies were found in our case. The conclusion. So corpus callosum or genesis may be asymptomatic or revealed by a highly polymorphic and nonspecific clinical feature. It should be researched in prenatal, postnatal and even in a dirt road. The diagnosis of corpus callosum can be performed during the prenatal or postnatal period. Prenatal diagnosis is commonly performed using USG between 8 to 22 weeks of gestation which might greatly reveal the component or partial defect as well as other indirect features such as two of genesis of corpus callosum. This approach must be complemented with a detailed structural USG and a prenatal MRI brain to confirm the presence of genesis of corpus callosum and other possible associated defects. And MRI brain could be repeated after birth to improve the screening of accompanying malformations. Our case was diagnosed on MRI where MRI brain imaging suggested the absence of other anomalies in this case. Thank you.