 This study investigated the correlation between C4D deposition in renal tissues and classes of lupus nephritis, ln. It was found that C4D deposition in glomerular capillaries of ln does not indicate the present disease activity, but may be a useful marker to predict the prognosis of ln. Additionally, it was observed that the presence of C4D indicates activation of the classical complement pathway in ln. Furthermore, it was noted that anti-DSDNA is a valuable test for disease activity and is correlated with C4D positive staining. This article was authored by Tahir Malakushan, Adhafea Muzgar, Majganisgri, and others.