 Advanced disease detection and prevention methods are crucial in minimizing crop losses due to pathogens and laboratory-based techniques such as PCR, IF, FISH, ELISA, FCM, and GCMS are direct detection methods, while indirect methods include thermography, fluorescence imaging, and hyperspectral techniques. Biosensors based on highly selective biorecognition elements are also a new tool for early identification of crop diseases. This article was authored by Yifan and Ramaraja P. Ramasamy.