 This study examined the effectiveness of hydroxyapatite as a treatment for dental hypersensitivity by evaluating its ability to block dental tubules and reduce dentin permeability. In vitro experiments demonstrated that hydroxyapatite can effectively occlude dental tubules and reduce dentin permeability, resulting in reduced sensitivity. These findings suggest that hydroxyapatite may be a viable option for treating dental hypersensitivity. This article was authored by Hashmed Kool, Muhammad Asad Gaffer, Muhammad Kaleem, and others.