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CHT™ Ceramic Hydroxyapatite for Commercial Purification

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Published on Jul 27, 2012

For more information, visit http://www.bio-rad.com/yt/1/CHT.
Bio-Rad's CHT media are innovative mixed-mode media that offer unique separation properties and unparalleled selectivity and resolution for a variety of molecules. CHT ceramic hydroxyapatite media are among the leading media for biomolecule purification. The spherical ceramic form of these crystalline hydroxyapatite media allow them to be used in production-scale columns at high flow rates while maintaining their unique separation properties. These media can be used at any stage in a process from initial capture to final polishing. Two types of CHT media are available in three particle sizes (20, 40, and 80 µm):

• Type I has a higher protein binding capacity and better capacity for acidic proteins
• Type II has a lower protein binding capacity but offers better resolution of nucleic acids and certain proteins; it also has a very low affinity for albumin and is particularly well-suited for the purification of many species and classes of immunoglobulins.

http://www.bio-rad.com/evportal/desti...

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