 Aptomers are short single-stranded DNA or RNA molecules that bind tightly to their target molecule. They are highly selective and can be used to detect abnormally high levels of two liver enzymes, alanine aminotransferase, ALT, and aspartate aminotransferase, AST, which are indicators of liver damage. These enzymes are detected using a lateral flow assay, LFA, device, which is a simple and cost-effective method for point-of-care applications. The aptomer-based LFA will be able to detect liver damage at an earlier stage, thus reducing the risk of long-term liver damage. This technology could potentially save millions of lives by providing an affordable and accessible solution for liver disease screening. This article was authored by Raja Chinapan, Tanvira Madmir, Suleiman Alsalama, and others.