 Beta blockers have been shown to be effective in reducing the risk of cardiovascular events in patients with heart failure with reduced ejection fraction, HFIEF. In this study, research has examined the effects of beta blockers on heart rate variability, HRV, in patients with HFPEF. They found that beta blockers increased the parasympathetic tone and decreased the sympathetic tone, resulting in improved HRV parameters and a lower risk of cardiac events during the morning hours when there is a sympathetic surge. This suggests that beta blockers may be beneficial in improving outcomes in patients with HFPEF. This article was authored by Shaza Salim, Asan H. Kandaka, Mohaned Al-Qadari, and others.