 The study found that the original Globerisk and score models overestimated the risk of cardiovascular mortality in Iranian populations, leading to a large number of people requiring interventions. These models can be recalibrated to more accurately predict the risk of cardiovascular mortality in Iranian populations. Globerisk showed better performance clinically, only among high-risk women. This article was authored by new Sinfa Hemfer, Akbar Fotuhi, Muhammad Ali Mantornia, and others.