 The literature review highlights the effectiveness of oral cholera vaccines, OCVs, in various settings including endemic, outbreak response and emergency situations. While two doses are recommended by manufacturers, a single dose would be easier to implement. Recent studies suggest that cold chain requirements may no longer be necessary, and a global OCV stockpile has been established for cholera preparedness. New killed and live attenuated vaccines are being explored as potential candidates for endemic settings and or travel as vaccine. The recent advances in cholera vaccination approaches should be considered in the global cholera control strategy, with the development of affordable cholera vaccines being a major success to improve cholera control.