 Deoxynivalinol, a don, a type of mycotoxin, is produced by certain types of fungi that cause fusarium, headlight, FHB. It is the most common and economically significant mycotoxin found in small grain crops around the world. Factors such as weather, soil fertility, and crop management can affect the amount of don present in grain. Regulatory and advisory standards have been established to limit the presence of don in food and feed. Strategies to reduce don levels in grain prior to harvesting and methods to mitigate its effects on human and animal health are also discussed. This article was authored by Stephen N. Weigulo.