 Monoclonal immunoglobulin deposition disease, MIDD, is a rare disorder characterized by the deposition of monoclonal antibodies in various organs, including the kidneys. It typically presents in middle age, but can also occur at younger ages. Symptoms include protonuria, hematuria, hypertension, and renal failure. Laboratory tests may show increased levels of IgM, Kappa light chains, and SS2 microglobulin. Flow cytometry testing can detect monoclonal plasma cells with Kappa light chain restriction and a Kappa to lambda ratio of 35 to 1. Renal biopsy shows nodular sclerosing glomerulopathy, while bone marrow biopsy may reveal plasma Cytoma. Treatments for MIDD include steroids and bortezomib. This article was authored by Sarmad said, Chad J. Cooper, Hasakaiosin Wosu, and others. We are article.tv, links in the description below.