 Genomic analysis using long reads is becoming increasingly popular, but the computational power required to process them can be prohibitive. To address this problem, researchers have developed an FPGA-based solution that integrates a novel alignment algorithm into an existing long-read, assembler. The resulting system is able to significantly reduce the time needed to process large amounts of data, while maintaining high levels of accuracy. This article was authored by Carolina Tong, Ranawi Jakejian, Jiang Chaowang and others.